Cancer antibodies.  Latest innovations and contributions from Israel

Cancer antibodies. Latest innovations and contributions from Israel

Jewish Connection – Like every week, Enlace Judío brings you the latest innovations and contributions in technology and healthcare from Start Up Nation Israel.

3D printed tissues for transplant

ITechnion has developed an innovative technology for culturing tissue for transplantation by printing tissue as support material in a microgel bath.

The new concept, called push and zoom, is based on an original concept developed by the researchers: CarGrowIt is a substance composed mainly of carrageenan and produced from red algae.

Tissue printing is an innovative approach to creating transplant tissue. Also called this technique bioprint, living cells are embedded in bio-ink and printed layer by layer. The printed tissue is then enlarged for days or weeks until it is ready for printing.

The peer-reviewed research, published in Advanced Science, was led by Professor Shulamit Levenberg of the School of Biomedical Engineering.

The major challenge in tissue engineering is to produce 3D structures with structural and functional properties that reproducibly and stably mimic the 3D environment of living tissue. According to the study, extrusion-based bioprinting has emerged as a valuable technique for fabricating cell-containing 3D scaffolds with high complexity and precision.

Researchers developed methods to prevent uneven shrinkage of printed fabric in the weeks after printing. The solution was found by changing the medium in which the tissue was printed and grown.

cancer antibodies

Cancer patients are testing a drug consisting of computer-designed antibodies “programmed” in Israel to “decide” whether the cells surrounding tumors are good or bad.

The aim of the study, Australia To evaluate the ability of antibodies to fight cells that help the tumor, and those that inhibit the growth of cancer to strengthen.

Yanay Ofranprofessor at university bar adHe has published numerous peer-reviewed studies on computer antibody design.

Rather than performing a single function, such as fighting a single virus, “nanorobots” can examine their environment and act differently towards different types of cells.

He noted that AU-007 was the first computer-designed antibody to enter a clinical trial.

Ofran designed the antibody at his company’s offices using artificial intelligence software Biological Designand being tested by the subsidiary Aulos Bioscience.

“What we do is use antibodies to identify cells they encounter, activate those that can attack the tumor, and stop those that are aiding it,” he explained.

Ofran He hopes his work will change scientists’ understanding of the potential of antibodies currently used to neutralize the coronavirus.

Aerobic exercise against cancer

A study conducted at Tel Aviv University revealed that regularly running or doing other types of aerobic exercise reduces the chance of developing certain types of cancer by 72%.

According to a peer-reviewed study recently published in the journal aerobic exercise, aerobic exercise makes certain organs so efficient at removing sugar from the body that tumors run out of glucose and are often unable to grow and spread. cancer research.

The investigation focused on: metastatic cancer, that is, cancer that has spread from its original location in the body. Scientists believe that exercise prevents primary tumors, but they focused on metastatic cancer because it is the leading cause of death in the world. Israel.

“Physical activity creates a hostile environment for tumors where they have a hard time getting glucose,” said the professor. carmite mortarof the Tel Aviv University Department of Human Genetics and Biochemistry.

“We all know that sports and physical exercise are good for our health. By looking at the internal organs, our study found that exercise changes the whole body, so cancer cannot spread.” tax.

heart failure alarm

A new Israeli app can sound an alarm before congestive heart failure starts by analyzing just a user’s voice.

in one study heart failure congestive with recovered patients hearOtechnology predicts 82% of relapses and catches them an average of 18 days before they occur.

hearO It “listens” to audio samples that users have recorded on their smartphones and warns them in case of potential danger. congestive heart failure. It works by detecting irregularities in a person’s speech and comparing them to the healthy “reference” voice. If abnormalities are detected, doctors are immediately notified so they can take preventive measures.

The new work was done by the company behind the app. Kordo Medical, in partnership with Beilinson Hospital, Barzilai Medical Center and Galilee Medical Center and Clalit Health Services Cardiovascular Centers. It is currently in the peer review process.

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